By Ethan Cerami

Advent The target of this e-book is to introduce XML to a bioinformatics viewers. It does so via introducing the basics of XML, record variety De?nitions (DTDs), XML Namespaces, XML Schema, and XML parsing, and illustrating those strategies with speci?c bioinformatics case stories. The publication doesn't think any prior wisdom of XML and is aimed toward those that need a strong advent to primary XML thoughts. The publication is split into 9 chapters: bankruptcy 1: creation to XML for Bioinformatics. This bankruptcy offers an advent to XML and describes using XML in organic information trade. A bird’s-eye view of our ?rst case research, the allotted Annotation process (DAS), is supplied and we study a pattern DAS XML rfile. The bankruptcy concludes with a dialogue of the professionals and cons of utilizing XML in bioinformatic purposes. bankruptcy 2: basics of XML and BSML. This bankruptcy introduces the basic suggestions of XML and the Bioinformatic series Markup Language (BSML). We discover the origins of XML, de?ne easy ideas for XML rfile constitution, and introduce XML Na- areas. We additionally discover a number of pattern BSML records and visualize those files within the TM Rescentris Genomic Workspace Viewer

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2. 4 Representing Sequence Features In addition to raw sequence data, BSML can also represent sequence features. A sequence feature is any piece of annotation that provides additional details regarding a specific location or range of sequence data. When we get to Chapter 6, we will spend more time formally defining sequence annotation, and discuss in detail the Distributed Annotation System (DAS). For now, it is simplest to think of sequence annotation as any piece of data that provides additional details regarding a raw sequence record.

For example, you can specify width and height attributes for an HTML img element or you can add a length attribute to a BSML Sequence element. You can specify as many attributes for an element as you need, and they need not be placed in any specific order. Attributes are always placed within the start tag and never within the end tag. com 24 XML for Bioinformatics XML requires that attribute values appear within quotes. You can use single quotes (') , or double quotes (") . For example, the following excerpt specifies an id attribute: ...

This chapter provides a comprehensive overview of reading and creating DTDs, along with specific applications to bioinformatics. We begin with a bird’s-eye view of a simple DTD for exchanging protein data, and explore several options for validating XML documents. We then dive into the specific details of DTD declarations, including the mechanics of declaring elements and attributes. We also explore the use of XML entities as a tool for creating reusable text and for building modular DTDs. Entities exist in several flavors, and this chapter describes when and how to use each one.

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XML for Bioinformatics by Ethan Cerami
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