By Patrick R. Gavin

Useful Small Animal MRI is the seminal reference for clinicians utilizing Magnetic Resonance Imaging within the prognosis and therapy of veterinary sufferers. even though MRI is used most often within the analysis of neurologic issues, it additionally has major program to different physique platforms. This ebook covers common anatomy and particular medical stipulations of the fearful procedure, musculoskeletal process, stomach, thorax, and head and neck. It additionally includes a number of chapters on affliction of the mind and backbone, together with inflammatory, infectious, neoplastic, and vascular ailments, along congenital and degenerative problems.

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CSF flow occurs in both directions (cranial and caudal), but primarily flows caudally in dogs. The pressure exhibited by the CSF contributes to intracranial pressure (ICP). The major site of CSF absorption is in the arachnoid villus within a venous sinus or a cerebral vein (deLahunta 1983). The villus is a prolongation of the arachnoid and the subarachnoid space into the venous sinus. Collections of these villi are known as arachnoid granulations. The venous endothelium acts like a ball valve (from transient transcellular channels that develop for the passage of fluid) so as to be open when CSF pressure exceeds the venous pressure (the normal relationship).

The ependymal lining of the ventricles is normally not apparent on both sequences, and is normally not enhanced following contrast administration. Normal choroid plexus, however, does contrast enhance following intravenous contrast administration. The blood-CSF barrier exists at the choroid plexus and consists of two cell layers separated by a thin basement membrane. 24. Pathologic specimen (ventral view (A)) of the dural meninges from a dog. The falx (larger arrows) and membranous tentorium cerebelli are shown (smaller arrows).

Sagittal T1-weighted MR image from a dog. The third (T), mesencephalic aqueduct (smaller arrows), and the fourth ventricle (larger arrows) are shown. membrane between the CSF and the plasma. The CSFextracellular fluid (ECF) barrier occurs over the outer surface of the brain and in the ventricles. This barrier is formed primarily by the ependymal cells. On the surface of the brain, a pial–glial membrane is present to limit exchange from the CSF and the nervous system parenchyma. Importantly, there is also a barrier between the vascular system and the brain parenchyma, termed the “blood brain barrier” (BBB).

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Practical Small Animal MRI by Patrick R. Gavin
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