By Janet F Eary; Winfried Brenner

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48) report on a needle track ulceration after radiation synovectomy of an ankle joint with Re-186, which showed healing by scar formation after a few weeks without any further treatment. Necrosis of periarticular tissue is the worst local complication in radiation synovectomy and is caused by accidental para-articular injection of the radionuclide. A very low frequency of two cases of necrosis out of 11,000 treatment procedures was reported by Kolarz and Thumb in 1982 (49). With at least 23,000 radiation synovectomy 34 Brenner procedures performed in Europe in 2001, there is only one documented case of radionecrosis in a knee joint after application of Y-90 (50).

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Hemarthrosis and synovitis associated with hemophilia: clinical use of P-32 chromic phosphate synoviorthesis for treatment. Radiology 1994; 190:257 – 261. 38. Siegel HJ, Luck JV Jr, Siegel ME, Quinones C. Phosphate-32 colloid radiosynovectomy in hemophilia: outcome of 125 procedures. Clin Orthop Relat Res 2001:409– 417. 39. Silva M, Luck JV Jr, Siegel ME. 32P chromic phosphate radiosynovectomy for chronic haemophilic synovitis. Haemophilia 2001; 7(suppl 2):40 – 49. 40. Kampen WU, Brenner W, Kroeger S, et al.

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Nuclear medicine therapy by Janet F Eary; Winfried Brenner
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