By Patrick J. Gullane, David P. Goldstein
Sataloff's complete Textbook of Otolaryngology: Head & Neck surgical procedure - Head & Neck surgical procedure is a part of a multi-volume textbook masking uncomplicated and scientific technological know-how around the whole box of otolaryngology. Volumes within the set comprise; otology, neurotology and skull-based surgical procedure; rhinology, hypersensitivity and immunology; facial plastic and reconstructive surgical procedure; laryngology and paediatric otolaryngology. the entire set is superior by way of over 5000 complete color photographs and illustrations, spanning approximately 6000 pages, whole with a entire index on DVD. Edited via Robert T Sataloff from Drexel collage collage of medication, Philadelphia, this quantity contains contributions from the world over recognized specialists in otolaryngology, making sure authoritative content material all through. Sataloff's finished Textbook of Otolaryngology: Head & Neck surgical procedure - Head & Neck surgical procedure is an essential, in-depth consultant to the sector for all otolaryngology practitioners. Key issues * Textbook of head and neck surgical procedure, a part of six-volume set overlaying the complete box of otolaryngology * Volumes comprise otology/neurotology, rhinology, cosmetic surgery, laryngology, and paediatric otolaryngology * Over 5000 complete color pictures and illustrations throughout six volumes * Edited via Robert T Sataloff, with contributions from the world over recognized otolaryngology specialists
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Early-responding tissues are characterized by a high α:β ratio, whereas late-responding tissues are characterized by a low α:β ratio. 7 Chapter 2: Principles of Radiation Oncology allowing several hours to elapse between individual doses, the shoulder region reappears after each incremental dose. This is due to repairing of sublethal damage during the elapsed interval between treatments. This has clinical importance in radiotherapy because dividing dose into fractions spares normal tissues as a function of repair of sublethal injuries between dose fractions.
Ionizing radiation can be categorized based on the nature of the particles making up the radiation. These various Chapter 2: Principles of Radiation Oncology particles have different ionization mechanisms and can be grouped as directly or indirectly ionizing. Directly ionizing radiation, such as charged particles, can ionize atoms directly through Coulomb forces if it carries sufficient kinetic energy. In contrast, neutral particles have less direct interaction with their target matter, and most of their ioni zation effects results from the production of secondary charged atomic particles, which themselves are directly ionizing when interacting with material.
Fig. 4: Relative dose as a function of depth in tissue shown for 60 Cobalt γ-rays, 22 MV X-rays, 200 kV X-rays, 22 MeV electrons, a proton Bragg peak and a Spread Out Bragg Peak. Source: Levy RP, Reinhard WM. Charged particle beams: technique and clinical experience. Transl Cancer Res. 2012;1:22-33. Protons are positively charged particles with a mass ~1835 times greater than that of electrons and have similar radiobiologic properties as conventional electrons or photon beams. Due to their relatively large mass, protons have little lateral side scatter in tissue.