By Walter Greene MD
This new compilation of Dr. Netter's recognized drawings contains the paintings of his proficient successors, who faithfully uphold the Netter culture of their skillful depiction of the most recent innovations and tactics. This new atlas-quality reference presents a vital review of pathophysiology, prognosis, and remedy of musculoskeletal problems. transparent and simple accompanying textual content describes the anatomy, uncomplicated technology, and basic ideas of evaluate and therapy that consultant each medical intervention.Features greater than 350 informative, superbly drawn illustrations both by means of, or within the variety of, Frank H. Netter, MD.Provides proper anatomy and easy technological know-how before everything of every bankruptcy to put the root for knowing the pathophysiology, prognosis, and therapy of every scientific condition.Covers person themes affecting the whole musculoskeletal procedure, resembling arthritic issues, fractures, rehabilitation, and nerve disorders.Organizes diagnostic and healing suggestions via area that will help you observe administration rules in perform.
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Extra resources for Netter's Orthopaedics (Netter Clinical Science)
Sample text
Symptomatic patients complain of fatigue, weakness, and a sense of cognitive difficulty (Figure 2-5). Kidney stones may be the first manifestation. However, advanced bony changes caused by bone resorption, such as brown tumors of long bones (radiolucent lesions secondary to very high levels of PTH) and subperiosteal resorption of the distal phalanges of the hand, are now rarely seen. The diagnosis of hyperparathyroidism is confirmed with an immunoassay for PTH. qxd 6/3/07 11:22 AM Page 30 Chapter 2 called osteitis fibrosa cystica.
Dark-skinned persons, however, require more prolonged exposure. Vitamin D2 (ergocalciferol) may be obtained through diet. Therefore, nutritional rickets is rare in countries that supplement milk and other food products with vitamin D2. Vitamins D2 and D3 undergo hydroxylation initially at the 25-position in the liver, then in the kidneys at the 1-position, to become 1,25-D3, a major calcium-regulating hormone. 1,25-D3 upregulates production of the calcium-binding proteins essential for calcium transport and absorption in the gut.
Therefore, nutritional rickets is rare in countries that supplement milk and other food products with vitamin D2. Vitamins D2 and D3 undergo hydroxylation initially at the 25-position in the liver, then in the kidneys at the 1-position, to become 1,25-D3, a major calcium-regulating hormone. 1,25-D3 upregulates production of the calcium-binding proteins essential for calcium transport and absorption in the gut. This hormone also stimulates bone resorption in a manner similar to PTH. Vitamin D–deficiency osteomalacia is seen primarily in elderly adults.