By Kim J. Burchiel
Surgical administration of ache, moment Edition, is a totally up to date cutting-edge reference on neurosurgical soreness administration. This re-creation is in complete colour and comprises the subsequent sections: Anatomic and Physiologic Foundations for Nociceptive and Neuropathic soreness, ache drugs, soreness Diagnoses, surgeries for discomfort, and New instructions for soreness surgical procedure. The chapters within the ebook specialize in strategies which are at present played through neurosurgeons to alleviate pain.
Key Features:
- Emphasizes most sensible facts remedy options
- loose on-line entry to video clips demonstrating surgical options defined within the book
- Explores nonsurgical and pharmacologic equipment of discomfort control
- Beautifully illustrated drawings express the knowledge of professional surgeons
This publication is a must have for all neurosurgeons treating sufferers struggling with acute and/or continual pain.
Includes bonus videos! subscribe to a unfastened account at http://mediacenter.thieme.com and upload this identify on your Favorites to view the videos.
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Additional resources for Surgical Management of Pain
Example text
Pain amplification by peripheral and central sensitization is a normal adaptive process. It is an integral aspect of the immune system response to injury and is mediated by familiar immune cells and chemical mediators. The resulting pain is typically transient, adaptive, and self-limiting. By amplifying pain, peripheral and central sensitization contribute to wound healing by reducing use of the injured body part. But things can go wrong. In the event of nerve injury and chronic inflammatory disease these processes can result in chronic intractable pain.
Targeting N-methyl-D-aspartate receptors for treatment of neuropathic pain. Expert Rev Clin Pharmacol 2011;4(3):379–388 39. Millan MJ. Descending control of pain. Prog Neurobiol 2002;66(6):355–474 40. Carlson JD, Maire JJ, Martenson ME, Heinricher MM. Sensitization of pain-modulating neurons in the rostral ventromedial medulla after peripheral nerve injury. J Neurosci 2007; 27(48):13222–13231 41. Cleary DR, Heinricher MM. Adaptations in responsiveness of brainstem pain-modulating neurons in acute compared with chronic inflammation.
48 ■⌀ Dorsal Column Stimulation: Segmental and Supraspinal Mechanisms The gate control theory proposed by Melzack and Wall in 196549 was an early attempt to explain the lack of a simple correlation between noxious stimulus intensity and pain sensation. Based on knowledge of dorsal horn projection neurons that responded to both noxious and innocuous peripheral stimuli and of descending inhibitory control of dorsal horn processing, the theory postulated a gate, comprising neurons in the substantia gelatinosa, that controlled throughput of somatosensory information to higher centers.