By Albert Altchek, Liane Deligdisch
The younger ob/gyn sufferer provides special difficulties various from the mature girl yet which education frequently neglects. This ordinary, functional booklet offers beneficiant insurance of all points of pre-womanhood gynecology. starting from the most typical difficulties to the fewer universal yet pressing, it emphasizes prognosis, specified care and administration all through.
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Extra info for Pediatric, Adolescent and Young Adult Gynecology
Sample text
The union of gametes determines gonadal differentiation which, in turn, determines the development of internal and external genitalia. It should be emphasized that male and female embryos contain primordial bipotential structures that could produce either male or female genitalia and that, under the influence of genetic and hormonal factors, will undergo differentiation. At about four weeks postconception, primordial germ cells migrate from the yolk sac to the urogenital ridge, which also contains undifferentiated cells that will become follicular or Sertoli cells and theca or Leydig cells.
Philadelphia, PA: Saunders, 2008. Stein MT, Sandberg DE, Mazur T, Eugster E, Daaboul J. A newborn infant with a disorder of sexual differentiation. J Dev Behav Pediatr 2004;25(5 suppl):S74–78. BLBK075-Altcheck January 16, 2009 4 11:55 CHAPTER 4 Diagnosis and Management of Congenital Adrenal Hyperplasia Karen Lin-Su, Saroj Nimkarn, & Maria I. New Mount Sinai School of Medicine and Hospital, New York, NY, USA Introduction Congenital adrenal hyperplasia (CAH) is a family of inherited errors of steroidogenesis, each disorder characterized by a specific enzyme deficiency that impairs normal steroid synthesis by the adrenal cortex.
Evidence demonstrates gender dissatisfaction in approximately 25% of patients with partial androgen insensitivity syndrome (PAIS), androgen biosynthetic defects and incomplete gonadal dysgenesis, regardless of whether reared as male or female. Available information supports assigning babies with micropenis to male gender (despite equivalent satisfaction reported whether assigned male or female) due to the fact that surgery would not be required and there is potential for fertility. In ovotesticular DSD, in which there is ovarian and testicular tissue, the decision should be based BLBK075-Altcheck January 16, 2009 11:53 22 CHAPTER 3 upon fertility potential according to the histology of the gonads and anatomy, provided that there is consistency with chosen sex.