By Kurt Benirschke, Graham J. Burton, Rebecca N Baergen
Pathology of the Human Placenta is still the authoritative textual content within the box and is revered and utilized by pathologists and obstetrician-gynecologists alike. Advances in genetics and molecular biology proceed to make the learn of the placenta considered one of sizeable diagnostic and criminal importance.New to this version is writer, Rebecca Baergen, M.D., leader of Perinatal and Pediatric Pathology on the big apple Hospital-Cornell sanatorium clinical heart and writer of the guide of Benirschke and Kaufmannв_Ts Pathology of the Human Placenta. The 5th variation displays new advances within the box and comprises 173 new colour illustrations.
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Additional info for Pathology of the human placenta.
Example text
Obstet. Gynecol. 84:1543–1567, 1962. : Choriocarcinoma: An “incidental finding” within a term placenta. Obstet. Gynecol. 21:96–101, 1963. , Garrett, W. : Placental aging monitored by gray scale echography. Amer. J. Obstet. Gynecol. 124:483–488, 1976. : Pathology of the Placenta. 2nd edition. Saunders, London, 1997. , Desoye, G. : Immunohistochemistry of two different types of placental fibrinoid. Acta Anat. 150:55–68, 1994. : Über “leere” Placentarhohlräume. Anat. Anz. 64: 65–73, 1927. : Placental calcification and maternal age.
In the case of a particularly broad and prominent subchorial closing ring, the specimen is called a placenta marginata. A placenta circumvallata is formed when the closing ring is peripherally undergrown by villous trees. In such cases, it does not represent the outermost margin of the placenta; rather, the membranes insert superficially from the fetal surface of the placenta. Placental shape and cord insertion are sometimes regarded as structurally impressive but functionally unimportant parameters.
This designation is the usual term applied to an increased appearance of seemingly polypoid trophoblastic outgrowths at the villous surfaces and to the trophoblastic bridges connecting neighboring villi. Only a small percentage of respective structures represents real trophoblast protrusions and real bridges in the third trimester (see Syncytial Knotting in Chapter 15). Rather, the vast majority are flat sections across trophoblastic surfaces of irregularly shaped and branched villi. Toward term, as well as under hypoxic conditions, the outer shape of terminal villi becomes more irregular, thus increasing the chance of trophoblastic flat sectioning (syncytial knotting).