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Vol. 66, No. 5, pp. 592-609. I. (2010). Oxidative stress in yeast, Biochemistry (Moscow), Vol. 75, No. 3, pp. 281-296. I. (2011). Adaptive response to oxidative stress: Bacteria, fungi, plants and animals, Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP, Vol. 153, No. 2, pp. 175-190. I. (2010). Regulatory protein Yap1 is involved in response of yeast Saccharomyces cerevisiae to nitrosative stress, Biochemistry (Moscow). Vol. 75, No. 5, pp. 629-664. I. V. (2005). Catalases protect cellular proteins from oxidative modification in Saccharomyces cerevisiae, Cell Biology International, Vol.
1982). Formation of NADPH, catalyzed by G6PDH and 6-phosphogluconate dehydrogenase in pentose phosphate pathway, is thought to serve for a general antioxidant defence, and is frequently described by scheme shown in Fig. 3. Fig. 3. Functional cooperation between G6PDH and GPx, explaining importance of G6PDH for erythrocyte survival. Abbreviations: SOD, superoxide dismutase; GPx, glutathione peroxidase; GR, glutathione reductase; G6PDH, glucose-6-phosphate dehydrogenase; GSH, reduced glutathione; GSSG, oxidized glutathione; NADP+, oxidized nicotineamide adenine dinucleotide phosphate; NADPH, reduced nicotineamide adenine dinucleotide phosphate; G6P, glucose-6-phosphate; 6PGL, 6-phosphogluconolactone.
2011). Adaptive response to oxidative stress: Bacteria, fungi, plants and animals, Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP, Vol. 153, No. 2, pp. 175-190. I. (2010). Regulatory protein Yap1 is involved in response of yeast Saccharomyces cerevisiae to nitrosative stress, Biochemistry (Moscow). Vol. 75, No. 5, pp. 629-664. I. V. (2005). Catalases protect cellular proteins from oxidative modification in Saccharomyces cerevisiae, Cell Biology International, Vol. 29, No.