By J. M. Grange (auth.), Marwali Harahap MD (eds.)
We have endeavoured during this publication to carry the reader updated info, so one can give a contribution to an superior skill to diagnose and deal with mycobacterial pores and skin ailments. This quantity is especially excited about conveying to dermatologists, microbiologists, immunologists, dermatologists in education, registrars in different specialties and kinfolk practitioners, a concise appraisal of a few contemporary advancements within the a number of facets of myco bacterial epidermis illnesses. The chapters facing bacteriology, pathology and immunology were deliberate to seem initially of the booklet to supply the required conceptual framework for the part on scientific technological know-how, which bargains with the range of medical states. the price of the medical descriptions is greatly superior by means of a cautious studying of the sooner chapters. The contributing authors were such a lot cooperative in making this, the 10th quantity within the New medical purposes in Dermatology sequence, an exceptional treatise. I thank each one of them for his or her tremendous contributions. If this publication stimulates and encourages a better curiosity in, and a greater figuring out of, mycobacterial dermis illnesses, and allows physicians to serve extra successfully those that undergo, the effort and time spent to provide it is going to be amply rewarded. PROFESSOR MARWALI HARAHAP IX sequence EDITOR'S FOREWORD It was once with nice excitement that I heard of Professor Harahap's desire to produce a quantity on mycobacterial pores and skin diseases.
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22, 542-5 35. Hirsh, B. C. and Johnson, W. C. (1984). Pathology of granulomatous disease. Epithelioid granulomas, part 1. Int. J. , 23, 237-46 36. Adams, D. O. (1976). The granulomatous inflammatory response: a review. Am. J. , 84, 164-91 37. Grange, J. M. (1982). Mycobacteria and the skin. Int. J. , 21, 497-503 38. Morrison, J. G. L. and Fourie, E. D. (1974). The papulonecrotic tuberculide from Arthus reaction to lupus vulgaris. Br. J. , 91, 263-70 39. Stanford, J. , Revill, W. D. , Gunthorpe, W.
THE IMMUNOLOGICAL SPECTRUM IN MYCOBACTERIAL DISEASE AND ITS RELEVANCE TO CUTANEOUS INFECTION There have been several attempts to classify cases of tuberculosis into a spectrum of activity according to clinical and immunological features, but with rather limited success. In contrast to leprosy, such spectra were not defined histologically owing to the difficulty in obtaining tissue in all cases except cutaneous ones. 3. Notably, all seven patients in Group 1 had cutaneous tuberculosis: either lupus vulgaris or solitary ulcerated lesions.
J. and Grange, J. M. (1975). The production and preliminary investigation of Burulin, a new skin test reagent for Mycobacterium ulcerans infection. J. , 74, 7-16 40. Hockmeyer, W. , Krieg, R. , Reich, M. and Johnson, R. D. (1978). Further characterization of Mycobacterium ulcerans toxin. Infect. , 21, 124-8 32 2 LEPROSY: BACTERIAL, PATHOLOGICAL, IMMUNOLOGICAL AND IMMUNOPATHOLOGICAL ASPECTS J. CONVtT and M. t. ULRICH THE BACTERIOLOGY OF MYCOBACTERIUM LEPRAE Introduction Mycobacterium leprae is recognized historically as the first pathogenic bacterium visualized in infected human tissues, as reported by the Norwegian physician Armauer Hansen in 1874.