By Allan Tsung, David A. Geller (auth.), Satdarshan P. S. Monga (eds.)

Molecular Pathology of Liver illnesses integrates the conventional wisdom of physiological and pathological procedures within the liver with a balanced emphasis on primary strategies; well timed advances in mobile and molecular mechanisms; and utilized pathology. The textbook is prepared into numerous sections, every one of along with an array of chapters that steadily and cohesively tricky on pertinent liver biology and pathology. the 1st 3 sections talk about the mobile composition of the liver besides their really good features, and extra dissect the molecular foundation of the mobile tactics which are so detailed to the liver. the following part examines the mechanisms which are normally implicated within the mobile and molecular foundation of a number of hepatic pathologies, finally via a bit every one on a mess of non-neoplastic and neoplastic ailments of the liver. Molecular Pathology of Liver ailments is a entire reference on liver pathobiology for simple, translational and medical researchers and physicians The layout of the quantity will function a prepared connection with appropriate issues within the liver, therefore offering a realistic disease-based integrative source at the molecular pathology of liver illness. Satdarshan (Paul) Singh Monga, MD is Director: department of Experimental Pathology and affiliate Professor of Pathology and drugs, college of Pittsburgh, Pittsburgh, PA

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Extra resources for Molecular Pathology of Liver Diseases

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This work was supported by INSERM, CNRS and the “Ligue Nationale Contre le Cancer” (LNCC, Comité de Paris, équipe Labellisée 2008), the ANR-07-PHYSIO and the CANCERSYS European network. Katz N, Teutsch HF, Jungermann K, Sasse D. Heterogeneous ­reciprocal localization of fructose-1, 6-bisphosphatase and of ­glucokinase in microdissected periportal and perivenous rat liver tissue. FEBS Lett. 1977;83(2):272–6. Jungermann K, Kietzmann T. Zonation of parenchymal and ­nonparenchymal metabolism in liver.

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Hepatology. 2006;43(3):407–14. Sekine S, Lan BY, Bedolli M, Feng S, Hebrok M. Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice. Hepatology. 2006;43(4): 817–25. Clevers H. Wnt/beta-catenin signaling in development and disease. Cell. 2006;127(3):469–80. Mosimann C, Hausmann G, Basler K. Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol. 2009;10(4):276–86. Nusse R, Fuerer C, Ching W, et al.

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Molecular Pathology of Liver Diseases by Allan Tsung, David A. Geller (auth.), Satdarshan P. S. Monga
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