By The Open University

This 12-hour loose direction defined the functionality of the cytoskeleton and its function within the shipping of vesicles among subcellular booths.

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1, 271 (1955). 31. Robertson, J. , J. Biophys. Biochem. Cytol. 3, 1043 (1957). 32. Robertson, J. , Biochem. Soc. Symp. ) 16, 3 (1959). 33. Robertson, J. , in "Progress in Biophysics, (B. Katz and J. A. V. ), pp. 343-418. Macmillan (Pergamon), 1960. 34. Robertson, J. ). Academic Press, New York, 1963. 35. Robertson, J. , Ciba Found. Symp. Principles Biomolecular Organization (1965). 36. Robertson, J. , Ann. Y. Acad. Sei. 137, 421 (1966). 37. Robertson, J. , in "Molecular Organization and Biological Function" (John M.

I t concerns both presumably permanent ergastoplasm and short-lived, temporary pinocytotic and phagocytotic vesicles. " The second type of transport includes traffic from nuclear regions to cytoplasm and ribosomes, from mitochondria to other surfaces, from ribosomes to cytoplasmic matrix, the movements of organelles, contraction, expansion, and flow of cytoplasmic ground substance and so forth. It concerns more or TABLE II. Intracellular Transport (IT) EXTRA—IT INTRA—IT Pinocytosis intake of water intake of nutrients translocation Diffusion—random preferential passive facilitated active Cytoplasmic movements streaming organelle movement surface plications Nuclear rotation less permanent organelles and protoplasmic ground matrix.

Changes in Membrane Permeability Chapman-Andresen and Holter showed that 14C-glucose is rapidly metabolized once it enters the vesicles, even though it does not pass through the external cell membrane [5]. In parallel with this change in membrane permeability, we have found that there is a great increase in the permeability of the membrane to water. , the permeability of the cell in the absence of active movements of membrane. This is in fact a more difficult problem than has been supposed, since most techniques do not distinguish between the entry of water attributable to membrane permeation and that resulting from membrane activity.

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Intracellular Transport by The Open University
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