By Peggy L. Carver (auth.), Astrid Sigel, Helmut Sigel, Roland K.O. Sigel (eds.)
MILS-13 offers an up to date assessment at the relationships among crucial metals and human illnesses, protecting thirteen metals and three metalloids: the majority metals sodium, potassium, magnesium, and calcium, plus the hint components manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of that are crucial for all times. additionally lined are chromium, vanadium, nickel, silicon, and arsenic, that have been proposed as being crucial for people within the second 1/2 the final century. notwithstanding, if in any respect, they're wanted in basic terms in ultra-trace quantities, and due to their occurrence within the surroundings, it's been tough to turn out whether they are required. as a minimum, these kinds of components are poisonous in better concentrations and consequently, shipping and mobile concentrations of a minimum of the fundamental ones, are tightly managed; accordingly, their homeostasis and function for all times, together with deficiency or overload, and their hyperlinks to health problems, together with melanoma and neurological issues, are completely mentioned. certainly, it truly is an outdated knowledge that metals are critical for all times. as a result, quantity thirteen presents in an authoritative and well timed demeanour in sixteen stimulating chapters, written by way of 29 across the world famous specialists from 7 international locations, and supported by means of greater than 2750 references, and over 20 tables and eighty illustrations, many in colour, a most modern view at the brilliant study sector of the Interrelations among crucial steel Ions and Human Diseases.
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Extra info for Interrelations between Essential Metal Ions and Human Diseases
Sample text
3 Role of Selenium in Other Infections ........................................................... 5 COPPER ............................................................................................................................ 1 Human Pharmacology and Pharmacokinetics .......................................................... 2 Role of Copper in Infectious Diseases ..................................................................... 1 Copper/Zinc Ratio ........................................................................................
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McDowell, and Nils G. Walter 7 Multiple Roles of Metal Ions in Large Ribozymes Daniela Donghi and Joachim Schnabl Contents of Volumes in the Metal Ions in Life Sciences Series 8 The Spliceosome and Its Metal Ions Samuel E. Butcher 9 The Ribosome: A Molecular Machine Powered by RNA Krista Trappl and Norbert Polacek 10 Metal Ion Requirements in Artificial Ribozymes that Catalyze Aminoacylations and Redox Reactions Hiroaki Suga, Kazuki Futai, and Koichiro Jin 11 Metal Ion Binding and Function in Natural and Artificial Small RNA Enzymes from a Structural Perspective Joseph E.