By Gisela Dallenbach-Hellweg, F.D. Dallenbach
Although the aim and scope of this monograph stay unchanged, i've been obliged to revise and rewrite many sections to maintain speed with the hot development in wisdom of endometrial pathology and body structure. New wisdom emanates from each zone, engendered through more advantageous meth ods of analysis in almost each subspecialty, by way of exemplary cooperation among disciplines, and particularly via the alternate of rules across the world. however, of illnesses is everchanging. a few, as soon as universal, develop into infrequent or perhaps disappear. Others all at once seem, exact and formerly unknown. elevated durability, smooth methods of dwelling and new tools of deal with ment have changed or augmented the scientific and diagnostic difficulties confront ing us. as a result, remedy with hormones and intrauterine birth control re ceive precise cognizance, commensurate with the significance afforded them at the present time. below the principle "nil nocere," the just about limitless makes use of for those brokers warrant that their results be conscientiously monitored by way of certain morphological stud ies, a prerequisite that succeeds merely whilst clinician and pathologist cooperate heavily. The sections on techniques for acquiring endometrial tissue, on steroid receptors, on practical disturbances, and on spontaneous abortion were replaced or multiplied to include new proof from contemporary discoveries that now seem major. purely time, besides the fact that, will turn out their actual worth. a lot of old curiosity within the textual content has been left intact, for "who desires to learn into the longer term, needs to seek advice the previous" (Andre Malraux).
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Extra info for Histopathology of the Endometrium
Sample text
Thus, we may find lipophages, siderophages, mucophages, cytophages, and others. Mast cells may also be found in the endometrium. FEYRTER (1957) believed they arose from the stroma. It seems more likely, however, that they infiltrate the endometrium from the circulating blood. , 1956); by others, more common in the secretory phase (SYLVEN, 1945; RUMBOLZ and GREENE, 1957; GUPTA and SCHUELLER, 1967). According to V ARA (1962) their number runs parallel with the height of the endometrium during the endometrial cycle.
Besides glycogen, the glandular cells also excrete neutral and acid mucopolysaccarides (SALM, 1962; STRAUSS, 1963), and lipids. Most accumulate at the apical cell-border and are either carboxymucins or sulphomucins (SORVARI, 1969). Fine droplets of non-double refractive lipids may be detected during the secretory phase, chiefly in the basal cytoplasm of the glandular epithelium. , 1941). Other authors (FROBOESE, 1924; CRAIG and DANZIGER, 1965), however, regard the lipid droplets as products of degeneration.
By the twenty-third and twenty-fourth day the granular endoplasmic reticulum has involuted. , 1959). During the secretory phase, as these microvilli draw back and disappear, the activity of alkaline phosphatase diminishes. The substance secreted by the glandular epithelial cells and found within the glandular lumina is chemically complex, and its composition varies with the phase of the menstrual cycle. During the proliferative phase it consists of a mixture of desquamated superficial glandular cells, RNA, proteins, and acid mucopolysaccharides.
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