By Centers for Disease Control and Prevention
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Additional resources for Emerging Infectious Diseases - Vol. 14, No.7, July 2008
Example text
Paul, MN, USA) was surgically removed from an asymptomatic patient identified in the prospective cohort study. Aseptic methods were used. The distal lumen opening was clamped with a sterile hemostat to retain the liquid within the lumen, and the catheter was placed in a sealed, sterile container and shipped overnight to CDC in Atlanta for processing within 24 hours of collection. At CDC, the CVC was placed into a Class II Biological Safety Cabinet, and a 1-cm segment was removed with a sterile scalpel.
Difficile may be a relatively common cause of community-associated disease. Despite evidence that only 20% of all human CDAD cases are community-associated (25,26), 6 (46%) of 13 human toxinotype V cases in our study were identified as CACDAD. The high prevalence of CA-CDAD among toxinotype V cases we found is consistent with other studies that have identified variant toxinotypes more frequently in CA-CDAD than in HCFA-CDAD (27,28). Toxinotype V strains may also be increasing as a cause of human CDAD since the emergence or recognition of epidemic toxinotype V disease in animals.
Wilcox MH, Cunniffe JG, Trundle C, Redpath C. Financial burden of hospital-acquired Clostridium difficile infection. J Hosp Infect. 1996;34:23–30. 1016/S0195-6701(96)90122-X Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13:818–29. 1097/00003246-198510000-00009 Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis.